Ctrl + Shift + N launches the default browser with the text on the clipboard as the url
Solution 1:
I had the exact same problem. Ctrl+Shift+N should create a new folder, but instead was opening a browser and pasting the clipboard. I realized it was being used by ClipX for navigtation. ClipX is a clipboard history application. You can right-click the ClipX icon in the tray and choose Configure. In the resulting window you can change that shortcut key association.
Solution 2:
Use ActiveHotkeys application , which will show you the current active hotkeys.
Solution 3:
Check to ensure you don't have any software installed that may be overriding the hotkey, such as AutoHotkey.