Windows 10 - windows open slow, GUI draw slows down with heavy multitasking - but why?

Windows 10 Fall Creators updates enabled by default Control Flow Guard (CFG) to all applications. Disabling this CFG force can also improve performance. To do this open the Windows Defender Security Center, now select App and browser control and click on Exploit Protection settings

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and now set the value for CFG to Off by Default

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Now reboot and Windows 10 should be faster.