How can I run multiple Skype accounts in one computer?
Run your first instance as usual, by clicking the icon.
Run the second one from terminal;
sudo /Applications/Skype.app/Contents/MacOS/Skype /secondary
I found the answer on this page. The command line arguments still exist, they have just been changed. Copying the format from this answer, we have the following command:
open -na /Applications/Skype.app --args --secondary --datapath="/Users/$(whoami)/Library/Application\ Support/Skype2"
Replace "Skype2" with as many numbers as you need instances of skype and go nuts.