file download by calling .ashx page
Your file is downloading, but you get it on javascript, on the data
parameter of your call because you call it with Ajax.
You use a handler - so ajax not needed here, and the most easy thing to do using javascript is that:
window.location = "FileDownload.ashx?parametres=22";
or with a simple link as
<a target="_blank" href="FileDownload.ashx?parametres=22" >download...</a>
Ah, and send the parameters via the url, you can not post them that way.
You can also read: What is the best way to download file from server