Solution 1:

sklearn.linear_model.LinearRegression will do it:

from sklearn import linear_model
clf = linear_model.LinearRegression()
clf.fit([[getattr(t, 'x%d' % i) for i in range(1, 8)] for t in texts],
        [t.y for t in texts])

Then clf.coef_ will have the regression coefficients.

sklearn.linear_model also has similar interfaces to do various kinds of regularizations on the regression.

Solution 2:

Here is a little work around that I created. I checked it with R and it works correct.

import numpy as np
import statsmodels.api as sm

y = [1,2,3,4,3,4,5,4,5,5,4,5,4,5,4,5,6,5,4,5,4,3,4]

x = [
     [4,2,3,4,5,4,5,6,7,4,8,9,8,8,6,6,5,5,5,5,5,5,5],
     [4,1,2,3,4,5,6,7,5,8,7,8,7,8,7,8,7,7,7,7,7,6,5],
     [4,1,2,5,6,7,8,9,7,8,7,8,7,7,7,7,7,7,6,6,4,4,4]
     ]

def reg_m(y, x):
    ones = np.ones(len(x[0]))
    X = sm.add_constant(np.column_stack((x[0], ones)))
    for ele in x[1:]:
        X = sm.add_constant(np.column_stack((ele, X)))
    results = sm.OLS(y, X).fit()
    return results

Result:

print reg_m(y, x).summary()

Output:

                            OLS Regression Results                            
==============================================================================
Dep. Variable:                      y   R-squared:                       0.535
Model:                            OLS   Adj. R-squared:                  0.461
Method:                 Least Squares   F-statistic:                     7.281
Date:                Tue, 19 Feb 2013   Prob (F-statistic):            0.00191
Time:                        21:51:28   Log-Likelihood:                -26.025
No. Observations:                  23   AIC:                             60.05
Df Residuals:                      19   BIC:                             64.59
Df Model:                           3                                         
==============================================================================
                 coef    std err          t      P>|t|      [95.0% Conf. Int.]
------------------------------------------------------------------------------
x1             0.2424      0.139      1.739      0.098        -0.049     0.534
x2             0.2360      0.149      1.587      0.129        -0.075     0.547
x3            -0.0618      0.145     -0.427      0.674        -0.365     0.241
const          1.5704      0.633      2.481      0.023         0.245     2.895

==============================================================================
Omnibus:                        6.904   Durbin-Watson:                   1.905
Prob(Omnibus):                  0.032   Jarque-Bera (JB):                4.708
Skew:                          -0.849   Prob(JB):                       0.0950
Kurtosis:                       4.426   Cond. No.                         38.6

pandas provides a convenient way to run OLS as given in this answer:

Run an OLS regression with Pandas Data Frame