Solution 1:

Currently (up-to-date Opera version is 53.0.2907.57), you can do the following:

  • go to the O main menu -> Settings
  • type "short" in the search box on the top to quickly find the Shortcuts settings
  • click Configure shortcuts button
  • type "dev" in the text box on the top to quickly find the Developer tools key binding.

This way you can see the current key binding and change the default Ctrl + Shift + I to more common F12 or whatever you like.

Solution 2:

go to easy setups --> settings --> and then scroll down to find "shortcuts". Choose "configure shortcuts" --> and then find "Developer Tools Console". If you scroll on the Developer Tools' row, you will see 'Type a shortcut' bar. Click that and press F12. And you can call "Developer Tools" with F12.